Strange Cases Of Twins With Different Parents

2021-02-01   |   by CusiGO

In August 2018, a man and a woman came to the laboratory of the population genetics and identification group at Columbia National University to examine the parentage of two male twins considered to be their children. This should have been a normal procedure for researchers who conduct thousands of similar tests every year, but it has turned into a strange and exciting case study. The analysis, published in the latest issue of the journal biomedical science, showed that the father’s genetic marker matched only one of the children. Research has confirmed that the twins have different biological parents.

Lilian Andrea Casas Vargas, Ph.D. in human genetics, Ph.D. in biological sciences and chief executive officer, said on the phone that she and her research team were very surprised to see the results of the DNA test, and they decided to start the whole process from scratch. “Because of the rarity of the case, we asked four people (mother, father and two children) to go back to the laboratory and collect blood samples for a second time,” Casas said. “In the end, we came to the same conclusion, which allowed us to make sure there were no procedural errors.”

In order to carry out maternal and paternity tests and obtain the personal data of the participants, the scientists sorted out the DNA samples, which are the genetic materials containing all the biological development and functional instructions. “The first thing we did in this case was to identify the child’s allele, the expression of a gene that matches the mother’s allele to exclude changes in the baby in the hospital,” Casas said. Once a link was established with the mother, the genetic information that the father should provide was reviewed. In this comparison, 21 genetic markers were measured to prove that the man was the father of the second pair of twins.

Casas claims that the scientific phenomenon in this case is called heterozygosity. It occurs when a second egg is released during the same menstrual cycle and fertilized by another man’s sperm during different sexual intercourse. In colloquial terms, Casas went on to say that what happened was that the woman had sex with two different men in a short period of time. About seven to 10 days, one egg was fertilized by one Lord and the other by another Lord.

Casas explained that it is relatively common for women to produce two or more eggs in a reproductive cycle. “There are genetic factors, biological factors, or some hormone therapy that can make this kind of superovulation frequent.” In this case, the mother of the twins has a genetic background because her family has twins.

In humans, super paternal fertilization is extremely rare. According to the research of Colombian scientists, there are about 19 cases known all over the world. In addition to the reported cases, they have also conducted a comprehensive review of the scientific literature on this phenomenon. “Three of these cases were found in 39000 records in a paternity database in the United States.”

Juan ram ó n ordo ó Ana, director of the Murcia twins registry, highlighted the rarity of the case. This kind of super fertilization is more common in animals, such as dogs and cats. For people, it’s strange, “odoniana said. “We don’t know how often it appears. We have only estimates. ” According to Spanish researchers and professor of genetics and behavioral evolution, only 2.4% of twins are born with different eggs, and their parents have some kind of parent-child relationship dispute, showing a super parent-child relationship. “It’s a very low proportion, even in couples who suspect their twin fathers.”

Oddly as the situation is, it has no effect on the development and healthy growth of the baby, odinana said. “Eight percent of these twins are produced in the process of super fertilization, that is, they are fertilized at different times, not in the same sexual relationship, but in the same father. It’s no problem for the children. They’re just two eggs, two sperm. In this case, the only difference is that they come from different parents, but the biological process is the same. It doesn’t have any special complications

Casas and odinana agree that although this case does not represent significant progress in scientific research, it is an interesting and necessary case report and will serve as a reference for future comparison. “There is very little serious literature on this human phenomenon. That’s the importance of our research, “Casas concluded.

Professor William usaquine Martinez, director of the population and identification Genetics Group at Columbia University, said, “Colombia conducts 11000 paternity tests every year. So far, there has been no case of heterosexual fertilization in science journals.” Martinez stressed that although paternity testing is a simple procedure, “due to its social and cultural influence, they have a huge emotional burden.”.

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